González-Hernández, R.A., Valdez-Cruz, N.A., Macías-Rubalcava, M.L., Trujillo-Roldán M.A.
Overview of fungal terpene synthases and their regulation.
World J Microbiol Biotechnol 39, 194 DOI: 10.1007/s11274-023-03635-y
2023
Valdez-Cruz, N. A., & Trujillo-Roldán, M. A.
Thermoinducible E. coli for Recombinant Protein Production in Inclusion Bodies.
In Inclusion Bodies: Methods and Protocols (pp. 17-30). New York, NY: Springer US
2023
Restrepo-Pineda S, Rosiles-Becerril D, Vargas-Castillo AB, Ávila-Barrientos LP, Luviano A, Sánchez-Puig N, García Hernández E, Pérez NO, Trujillo-Roldán MA, Valdez-Cruz NA.
Induction temperature impacts the structure of recombinant HuGM-CSF inclusion bodies in thermoinducible E. coli.
Electronic Journal of Biotechnology.59: 96-106 DOI: 10.1016/j.ejbt.2022.08.004. [2021 journal impact factor 2.826]
2022
Serrano-Carreón L, Aranda-Ocampo S, Balderas-Ruíz KA, Juárez AM, Leyva E, Trujillo-Roldán MA, Valdez-Cruz NA, Galindo E.
A case study of a profitable mid-tech greenhouse for the sustainable production of tomato, using a biofertilizer and a biofungicide.
Electronic Journal of Biotechnology. DOI: 10.1016/j.ejbt.2022.06.003
2022
Avila-Barrientos LP, Cofas-Vargas LF, Agüero-Chapin G, Hernández-García E, Ruiz-Carmona S, Valdez-Cruz NA, Trujillo-Roldán MA, Weber J, Ruiz-Blanco YB, Barril X, Garcia-Hernandez E.
Computational design of inhibitors targeting the catalytic subunit of Escherichia coli FOF1-ATP synthase.
Antibiotics 11(5):557; DOI: 10.3390/antibiotics11050557 [2020 journal impact factor 4.639]. Online ISSN: 2079-6382
2022
Restrepo-Pineda S, Sánchez-Puig N, Pérez NO, García-Hernández E, Valdez-Cruz NA, Trujillo-Roldán MA*.
The pre-induction temperature affects recombinant HuGM-CSF aggregation in thermoinducible Escherichia coli.
Applied Microbiology and Biotechnology. DOI: 10.1007/s00253-022-11908-z. ISSN: 0175-7598 (print); 1432-0614 (web) [2020 journal impact factor 4.813]
2022
Pérez-Rodriguez S., Reynoso-Cereceda GI, Valdez-Cruz NA, Trujillo-Roldán MA*.
A comprehensive comparison of mixing and mass transfer in shake flasks and their relationship with MAb productivity of CHO cells.
Bioprocess and Biosystems Engineering. DOI: 10.1007/s00449-022-02722-y. [2020 journal impact factor 3.210]
2022
Posadas D, Palacios C, Zenit R, Blancas-Cabrera A, Trujillo-Roldán MA, Salinas M, Ascanio G.
Flow patterns of multiple axial-radial impellers for potential use in aerated stirred tanks.
Chemical Engineering & Technology. DOI: 10.1002/ceat.202100521. [2020 journal impact factor 1.728]. Online ISSN:1521-4125
2022
Campos-López A, Uribe-López JA, Cázares-Ordoñez V, Garibay-Orijel R, Valdez-Cruz NA, Trujillo-Roldán MA.
Quercetin and 1-methyl-2-oxindole mimic root signaling that promotes spore germination and mycelial growth of Gigaspora margarita.
Mycorrhiza. DOI: 10.1007/s00572-022-01074-5. Electronic ISSN 1432-1890, Print ISSN 0940-6360 [2020 journal impact factor 3.387]
2022
Vargas-Zapata JD, Vargas-Zapata A, Ramírez-Vargas JF, Valdez-Cruz NA, Trujillo-Roldán MA, Orozco-Sánchez F.
Development and characterization of an alternative control system to study separately oxygen and momentum transfer effects in stirred tank bioreactors.
Revista Mexicana de Ingeniería Química. 21(1):Proc2607. DOI: 10.24275/rmiq/Proc2607. ISSN 2395-8472. [2020 journal impact factor 2.148]
2022
Valdez-Cruz NA, Orozco-Sánchez F, Rodríguez-Monroy M, Busto VD, Trujillo-Roldán MA *.
Enseñanza de la operación en biorreactores y el escalamiento de bioprocesos: capacitación multidisciplinaria en un curso teórico-práctico.
Revista Educación en Ingeniería. 17(33), pp. 79-85. https://educacioneningenieria.org/index.php/edi/article/view/1153/1037
2022
García-Cabrera RI, Valdez-Cruz NA, Daniel-Vázquez A, Blancas-Cabrera A, Trujillo-Roldán MA.
Roles of culture media and oxygen transfer in the scale-up from shake flasks to pneumatic bioreactor of the plant growth-promoting bacterium Rhizobium phaseoli.
Revista Mexicana de Ingeniería Química. 20(2); 1093-1111
DOI: 10.24275/rmiq/Bio2297. ISSN 2395-8472.
2021
Balderas-Ruíz KA, Gómez-Guerrero CI, Trujillo-Roldán MA, Valdez-Cruz NA, Aranda-Ocampo S, Juárez AM, Leyva E, Galindo E, Serrano-Carreón L.
Bacillus velezensis 83 increases productivity and quality of tomato (Solanum lycopersicum L.): pre and postharvest assessment.
Current Research in Microbial Sciences, 2121.
DOI: 10.1016/j.crmicr.2021.100076
2021
Restrepo-Pineda S, Pérez NO, Valdez-Cruz NA, Trujillo-Roldán MA. Thermoinducible expression system for producing recombinant proteins in Escherichia coli: advances and insights.
FEMS Microbiology Reviews, DOI: 10.1093/femsre/fuab023
2021
Valdez-Cruz NA, García-Hernández E, Espitia C, Cobos-Marín L, Altamirano C, Bando-Campos CG, Cofas-Vargas LF, Coronado-Aceves EW, González-Hernández RA, Hernández-Peralta P, Juárez-López D, Ortega-Portilla PA, Restrepo-Pineda S, Zelada-Cordero P, Trujillo-Roldán MA*.
Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment. Microbial Cell Factories.
20, 88. DOI: 10.1186/s12934-021-01576-5
2021
Pérez-Rodriguez S, Wulff T, Gunnar Voldbor B, Altamirano C, Trujillo-Roldán MA, Valdez-Cruz NA.
Compartmentalized proteomic profiling outlines the crucial role of the Classical Secretory Pathway during recombinant protein production in Chinese hamster ovary cells.
ACS Omega DOI: 10.1021/acsomega.0c06030
2021
Pérez-Rodriguez S, Ramírez-Lira MJ, Wulff T, Gunnar Voldbor B, Ramírez OT, Trujillo-Roldán MA, Valdez-Cruz NA.
Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis.
PLoS ONE 15(8): e0237930. doi: 10.1371/journal.pone.0237930
2020
Ortega-Quintana FA, Trujillo-Roldán MA, Botero-Castro H, Alvarez H.
Modeling the interaction between the central carbon metabolism of Escherichia coli and bioreactor culture media.
Biochemical Engineering Journal. 163:107753. doi: 10.1016/j.bej.2020.107753
2020
Pérez-Rodriguez S, Ramírez OT, Trujillo-Roldán MA, Valdez-Cruz NA.
Comparison of protein precipitation methods for sample preparation prior to proteomic analysis of Chinese hamster ovary cell homogenates.
Electronic Journal of Biotechnology. doi: 10.1016/j.ejbt.2020.09.006. I.F.: 2.894
2020
García-Cabrera RI, Valdez-Cruz NA, Blancas-Cabrera A, Trujillo-Roldán MA.
Oxygen transfer affect polyhydroxybutyrate production and oxidative stress response in submerged cultures of Rhizobium phaseoli.
Biochemical Engineering Journal. 162:107721. doi: 10.1016/j.bej.2020.107721. I.F.: 3.475
2020
Pérez-Rodriguez S, Ramírez-Lira MJ, Trujillo-Roldán MA, Valdez-Cruz NA.
Nutrient supplementation stimulates culture longevity, monoclonal antibody production and oxidative metabolism of Chinese hamster ovary cells.
Bioengineered 11(1):463-471. doi: 10.1080/21655979.2020.1744266. IF 1.544. Print ISSN: 2165-5979 Online ISSN: 2165-5987. I.F.: 2.205
2020
Ángeles-Argáiz RE, Carmona-Reyes IA, Quintero-Corrales CA, Medina-Macías FJ, Blancas-Cabrera A, Valdez-Cruz NA, Ulloa M, Trujillo-Roldán MA, Garibay-Orijel R.
From field sampling to pneumatic bioreactor mycelia production of the ectomycorrhizal mushroom Laccaria trichodermophora.
Fungal Biology 124:205-218. doi: 10.1016/j.funbio.2020.02.003. IF. 2.789
2020
Arregui L, Ayala M, Gómez-Gil X, Gutiérrez-Soto G, Hernández-Luna CE, Herrera de los Santos M, Levin L, Rojo-Domínguez A, Romero-Martínez D, Saparrat MCN, Trujillo-Roldán MA, Valdez-Cruz NA.
Laccases: structure, function, and potential application in water bioremediation.
Microbial Cell Factories 18:200. DOI: 10.1186/s12934-019-1248-0
2019
Restrepo-Pineda S, Bando-Campos CG, Valdez-Cruz NA, Trujillo-Roldán MA*
Recombinant production of ESAT-6 antigen in thermoinducible Escherichia coli: The role of culture scale and temperature on metabolic response, expression of chaperones, and architecture of inclusion bodies.
Cell Stress and Chaperones. IF. 2.571. doi.org/10.1007/s12192-019-01006-x.
2019
Gamboa-Suasnavart RA, Marín-Palacio LD, López-Griego L, Córdova-Aguilar MS, Valdez-Cruz NA, Trujillo-Roldán MA*
Volumetric power input as a reliable parameter for scale-up from shake flask to stirred-tank bioreactor: production of a recombinant glycoprotein by Streptomyces lividans.
Revista Mexicana de Ingeniería Química. 18, (3) 1083-1097. I.F.: 0.924.
2019
Bando-Campos G, Juárez-López D, Román-González SA, Castillo-Rodal AI, Olvera C, López-Vidal Y, Arreguín-Espinosa R, Espitia C, Trujillo-Roldán MA, Valdez-Cruz NA.
Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection.
Microbial Cell Factories. 18:11. Doi: 10.1186/s12934-019-1059-3. I.F. 3.831.
2019
De Marco A, Ferrer-Miralles N, Garcia-Fruitós E, Mitraki A, Peternel S, Rinas U, Trujillo-Roldán MA, Valdez-Cruz NA, Vázquez E, Villaverde A.
Bacterial inclusion bodies are industrially exploitable amyloids. FEMS Microbiology Reviews.
43(1) 53-72, fuy038. doi: 10.1093/femsre/fuy038. I.F. 12.198. Online ISSN 1574-6976 Print ISSN 0168-6445.
2019
Gamboa-Suasnavart RA, Valdez-Cruz NA, Gaytan-Ortega G, Reynoso-Cereceda GI, Cabrera-Santos D, López-Griego L, Klöckner W, Büchs J, Trujillo-Roldán MA.
The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks.
Microbial Cell Factories. 17:189. DOI: 10.1186/s12934-018-1035-3. I.F. 3.831.
2018
Carlos Calcines-Cruz, Alejandro Olvera, Ricardo M. Castro-Acosta, Guadalupe Zavala, Alejandro Alagón, Mauricio A. Trujillo-Roldán, and Norma A. Valdez-Cruz.
Recombinant-phospholipase A2 production and architecture of inclusion bodies are affected by pH in Escherichia coli.
International Journal of Biological Macromolecules doi:10.1016/j.ijbiomac.2017.10.178
2017
Greta I. Reynoso-Cereceda, María S. Córdova-Aguilar, Norma A. Valdez-Cruz, Mauricio A. Trujillo-Roldán*
Shaken flasks by resonant acoustic mixing in the biosynthesis of alginate by Azotobacter vinelandii with non-Newtonian rheological characteristics.
Journal of Chemical Technology & Biotechnology doi: 10.1002/jctb.5475
2017
Norma A. Valdez-Cruz*, Greta I. Reynoso-Cereceda, Saumel Pérez-Rodríguez, Sara Restrepo-Pineda, Jesús González-Santana, Alejandro Olvera, Guadalupe Zavala, Alejandro Alagón, and Mauricio A. Trujillo-Roldán
Production of a recombinant phospholipase A2 in Escherichia coli using resonant acoustic mixing that improves oxygen transfer in shake flasks.
Microbial cell Factories. 16:129. doi: 10.1186/s12934-017-0746-1
2017
Andrea Bedoya-López, Karel Estrada, Alejandro Sanchez-Flores, Octavio T. Ramírez, Claudia Altamirano, Lorenzo Segovia, Juan Miranda-Ríos, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz.
Effect of temperature downshift on transcriptomic responses of Chinese hamster ovary cells during recombinant tPA production cultures
PLoS One. Online ISSN: 1932-6203. F. 3.234. 11(3):e0151529. doi: 10.1371/journal.pone.0151529
2016
Reynoso-Cereceda GI, Garcia-Cabrera RI, Valdez-Cruz NA, Trujillo-Roldán MA
Shaken flasks by Resonant Acoustic Mixing versus orbital mixing: Mass transfer coefficient kLa characterization and Escherichia coli cultures comparison
Biochemical Engineering Journal. 105: 379-390
2016
Mancilla E, Palacios-Morales CA, Cordova-Aguilar MS, Trujillo-Roldán MA, Ascanio G, Zenit R
A hydrodynamic description of the flow behavior in shaken flasks
Biochemical Engineering Journal 99:61-66
2015
Carrasco-Espinosa K, García-Cabrera RI, Bedoya-López A, Trujillo-Roldán MA, Valdez-Cruz NA
Positive effect of reduced aeration rate on growth and stereospecificity of DL malic acid consumption by Azospirillum brasilense: improving the shelf life of a liquid inoculant formulation
Journal of Biotechnology 195:74-81
2015
Mauricio A. Trujillo-Roldán *, Angélica M. Cuesta-Álvarez, John Fredy Monsalve-Gil and Norma A. Valdez-Cruz
Impact of the carbon source on the production, molecular weight and viscosifying power of alginate by Azotobacter vinelandii
DYNA-COLOMBIA (in press)
2015
Andrea Castellanos-Mendoza, Ricardo M Castro-Acosta, Alejandro Olvera, Guadalupe Zavala, Miguel Mendoza-Vera, Enrique García-Hernández, Alejandro Alagón, Mauricio A Trujillo-Roldán and Norma A Valdez-Cruz
Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli
Microbial Cell Factories, 13:137
2014
Luz D. Marín-Palacio, Ramsés A. Gamboa-Suasnavart, Norma A. Valdez-Cruz, Luis Servín-González, Ma. Soledad Córdova-Aguilar, Enrique Soto, Wolf Klöckner, Jochen Büchs and Mauricio A. Trujillo-Roldán
The role of volumetric power input in the growth, morphology, and production of a recombinant glycoprotein by Streptomyces lividans in shake flask cultures
Biochemical Engineering Journal doi: DOI: 10.1016/j.bej.2014.06.010.
2014
Monserrat García-García, Leticia Rocha-Zavaleta, Norma A. Valdez-Cruz, Mauricio A. Trujillo-Roldán
Conservation of the mycelia of the medicinal mushroom Humphreya coffeata
(Berk.) Stey. in sterile distilled water, MethodsX 1:19-22.
2014
Mauricio A. Trujillo-Roldán *, Norma A. Valdez-Cruz, César Gonzalez-Monterrubio, Eduardo V. Acevedo-Sánchez, Carlos Martínez-Salinas, Ramsés I. García-Cabrera, Ramsés A. Gamboa-Suasnavart, Luz D. Marín-Palacio, Jesús Villegas, Abel Blancas-Cabrera
Scale-up from shake flasks to pilot-scale production of the plant growth-promoting bacterium Azospirillum brasilense for preparing a liquid inoculant formulation
Applied Microbiology and Biotechnology, 97:9665–9674 . ISSN: 0175-7598. IF. 3.689
2013
Gamboa-Suasnavart RA, Marín-Palacio LD, Martínez-Sotelo JA, Espitia C, Servín-González L, Valdez-CruzNA, Trujillo-Roldán MA *.
Scale-up from shake flasks to bioreactor, based on power input and Streptomyces lividans morphology, for the production of recombinant APA (45/47kDa protein) from Mycobacterium tuberculosis.
World J Microbiol Biotechnol. 10 Mar.
2013
Daniel Aguilar-Salvador, Isabel Angeles-Santander, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz.
Biología Sintética: diseñando sistemas biológicos con piezas genéticas.
Revista de Biotecnología. Vol 16, no 1.
2012
Valdez Cruz NA., Romo Buchelly RJ., Álvarez AC., Trujillo-Roldán MA *
Desde el gen hasta el biorreactor en la producción de proteínas recombinantes. Libro Escalado de bioprocesos y entrenamiento en operación de biorreactores.
Capítulo 11, pp. 104-123. ISBN 978-958-761-203-5.
2012
Ramsés A. Gamboa-Suasnavart, Norma A. Valdez-Cruz, Laura E. Cordova-Dávalos, José A. Martínez-Sotelo, Luis Servín-González, Clara Espitia, Mauricio A. Trujillo-Roldán *
The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks
Microbial Cell Factories, 10:110. ISSN. 1475-2859, I.F.: 3.55
2011
Norma A. Valdez-Cruz, Octavio T. Ramirez and Mauricio A. Trujillo-Roldán *
Molecular responses of Escherichia coli caused by heat stress and recombinant protein production during temperature induction
Bioengineered Bugs, 2: 2, Pages 105 – 110. ISSN. 1949-1018. Indexed in PubMed/Medline.
2011
Tóshiko Takahashi-Iñiguez, Humberto García-Arellano, Mauricio A. Trujillo-Roldán, María Elena Flores
Protection and reactivation of human methylmalonyl-CoA mutase by MMAA
Biochemical and Biophysical Research Communications 404: 443-447. ISSN. 0006-291X, I.F.: 2.484
2011
Ana María Zapata-Vélez and Mauricio A. Trujillo-Roldán *
The lack of a nitrogen source and/or the C/N ratio affects the molecular weight of alginate and its productivity in submerged cultures of Azotobacter vinelandii.
Annals of Microbiology. 60 (4) 661-668. ISSN. 1590-4261, I.F.: 0.689
2010
Norma A. Valdez-Cruz, Luis Caspeta, Néstor Pérez, Octavio T. Ramírez and Mauricio A. Trujillo-Roldán *
Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoter
Microbial Cell Factories. 9:18. (Number 11 in the Top 20 most accessed articles in 2010). ISSN. 1475-2859, I.F.: 3.55
2010
Sandra M. Porras-Arboleda, Norma A. Valdez-Cruz, Benjamín Rojano, Cecilia Aguilar, Leticia Rocha-Zavaleta and Mauricio A. Trujillo-Roldán *
Mycelial Submerged Culture of New Medicinal Mushroom, Humphreya coffeata (Berk.) Stey. (Aphyllophoromycetideae) for the Production of Valuable Bioactive Metabolites with Cytotoxicity, Genotoxicity, and Antioxidant Activity.
International Journal of Medicinal Mushrooms 11(4):335-350. ISSN. 1521-9437. I.F.: 0.895
2009
Mauricio A. Trujillo-Roldán * y Norma A. Valdez-Cruz
The use of disposable bioreactors in the biopharmaceutical industry and its implications on engineering. DYNA-COLOMBIA
Revista de la Facultad de Minas de la Universidad Nacional de Colombia. Sede Medellín. (158): 275-283.
2009
